I'm a big fan of Welcome to Night Vale, the podcast. I was able to go to a live show last month and had such a great time.
The book was fun. There were a lot of moments that really made me laugh. I did feel like the absurdity in the book, which works so well in the podcast, had trouble holding my attention in the novel. I think it would have worked better as a short story. There were a lot of moments in the book in which I was really attached to what was happening, and needed to know what would happen next, but then they tended to be followed with sections I had trouble immersing myself in. My mind would wander and I had trouble motivating myself to stick with it.
It is an enjoyable story, and I absolutely recommend it to all fans of Welcome to Night Vale. If you're unfamiliar with it, I'm not as sure you would enjoy this. I would suggest you check out the free podcast and then decide.